A game babes play with everyone (8)
I believe the answer is:
baseball
'a game' is the definition.
(baseball game is a kind of game)
'babes play with everyone' is the wordplay.
'play with' indicates anagramming the letters (I've seen 'played with' mean this (I've seen this in other clues)).
'everyone' becomes 'all' (all people).
'babes' is an anagram of 'baseb'.
'baseb'+'all'='BASEBALL'
(Other definitions for baseball that I've seen before include "Nine-a-side game" , "Bale labs out for this game" , "American team gave" , "Summer sport of US" , "Game played badly in the sable lab" .)