Ache (4)
I believe the answer is:
pain
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">ache</span>' is the definition.<br/ ><span class="explanation-format__explanation">(I've seen this in another clue)</span><br/ ><br/ >This is the entire clue.<br/ ></span>
(Other definitions for pain that I've seen before include "Hurt feeling" , "nuisance to be put up with" , "Suffering, ache" , "Suffering, distress" , "Tiresome figure" .)