Crossword Genius

Alienate (8)

Ross

I believe the answer is:

estrange

<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">alienate</span>' is the definition.<br/ ><span class="explanation-format__explanation">(I know that alienate can be written as estrange)</span><br/ ><br/ >This is all the clue.<br/ ></span>

(Other definitions for estrange that I've seen before include "Anger set (anag.)" , "As Regent (anag.)" , "Lose friendship" , "Reagents (anag.)" , "disunity" .)

I've seen this clue in the Evening Standard, The Daily Mail, The Times, The Sun and the Penny Press.
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