Alienation (12)
I believe the answer is:
estrangement
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">alienation</span>' is the definition.<br/ ><span class="explanation-format__explanation">(I know that alienation can be written as estrangement)</span><br/ ><br/ >This is the entire clue.<br/ ></span>
(Other definitions for estrangement that I've seen before include "division" , "Alienation" , "Result of splitting up" , "lack of good relationship" .)