Being run out for a single means disaster (4)
I believe the answer is:
ruin
'disaster' is the definition.
(ruin can mean disaster or catastrophe)
'being run out for a single' is the wordplay.
'being run' becomes 'r' (cricket abbreviation).
'out' is an insertion indicator.
'for' becomes 'un' (I can't explain this - if you can you should give a lot more credence to this answer).
'a single' becomes 'I' (I as in one).
'un' placed around 'i' is 'uin'.
'r'+'uin'='RUIN'
'means' acts as a link.
Can you help me to learn more?
(Other definitions for ruin that I've seen before include "State of devastation and destruction" , "Destruction or bankruptcy" , "Wrecked building" , "Wreck" , "fall" .)