Crossword Genius

Big vessel (5)

Ross

I believe the answer is:

aorta

<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">big vessel</span>' is the definition.<br/ ><span class="explanation-format__explanation">(I've seen this in another clue)</span><br/ ><br/ >This is all the clue.<br/ ></span>

(Other definitions for aorta that I've seen before include "Major blood vessel" , "Bloody channel" , "sort of vessel" , "vital transporter" , "Principal artery" .)

I've seen this clue in the Newsday and The Guardian.
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