Bother, inconvenience (6)
I believe the answer is:
hassle
<span class="explanation-format__ClueExplanation">I believe this clue is a double definition.<br/ ><br/ >'<span class="explanation-format__original">bother</span>' is the first definition.<br/ ><span class="explanation-format__explanation">(synonyms)</span><br/ ><br/ >'<span class="explanation-format__original">inconvenience</span>' is the second definition.<br/ ><span class="explanation-format__explanation">(I've seen this in another clue)</span><br/ ><br/ ></span>
(Other definitions for hassle that I've seen before include "Colloquial harassment or annoyance" , "Les has (anag) - a great deal of trouble" , "badger" , "problem" , "Modern word for bother and annoyance" .)