Case of lascivious American with Epstein essentially filling cravings (5)

'cravings' is the definition.
(I've seen this in another clue)

'case of lascivious american with epstein essentially filling' is the wordplay.
'case of' suggests removing the centre (like emptying a case).
'american' becomes 'US' (abbreviation for United States).
'with' says to put letters next to each other.
'essentially' indicates the central letters.
'filling' indicates putting letters inside.
'lascivious' with its centre removed is 'ls'.
The middle of 'epstein' is 't'.
'us'+'t'='ust'
'ls' going around 'ust' is 'LUSTS'.