Children's magazine (5)
'children's magazine' is the definition.
(I've seen this before)
This is the entire clue.
(Other definitions for comic that I've seen before include "publication for children" , "Amusing, laughable" , "Funny man, maybe stand-up" , "Causing laughter" , "Funny man, may be stand-up" .)
I believe this is a double definition.
'children's' is the first definition.
(issue can mean someone's offspring)
'magazine?' is the second definition.
(I've seen this before)
(Other definitions for issue that I've seen before include "Major topic for debate" , "Important topic for offspring" , "litter" , "Problem - child" , "Give or send out" .)