City on the Rhone (4)
I believe the answer is:
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">city on the rhone</span>' is the definition.<br/ ><span class="explanation-format__explanation">(I've seen this before)</span><br/ ><br/ >This is the entire clue.<br/ ></span>
(Other definitions for lyon that I've seen before include "City of south-central France" , "French city on the Rhone" , "River port of southeast France" , "River port, capital of the Rhone department" , "City where the Saone joins the Rhone" .)