Closed sac
I believe the answer is:
cyst
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">closed sac</span>' is the definition.<br/ ><span class="explanation-format__explanation">(I've seen this in another clue)</span><br/ ><br/ >This is all the clue.<br/ ></span>
(Other definitions for cyst that I've seen before include "Fluid filled sac" , "Sac in the body containing liquid secretion" , "Abnormal body cavity" , "Abnormal sac formed on or in the body" , "Abnormal membranous sac" .)