Cry of despair (4)
I believe the answer is:
alas
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">cry of despair</span>' is the definition.<br/ ><span class="explanation-format__explanation">(I've seen this in another clue)</span><br/ ><br/ >This is all the clue.<br/ ></span>
(Other definitions for alas that I've seen before include "Expression of regret" , "More's the pity" , "Cry of regret" , "What a shame!" , "Exclamation of grief" .)