Derange (7)
I believe the answer is:
unhinge
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">derange</span>' is the definition.<br/ ><span class="explanation-format__explanation">(synonyms)</span><br/ ><br/ >This is all the clue.<br/ ></span>
(Other definitions for unhinge that I've seen before include "Cause to become mentally unbalanced like dislodged door" , "Unbalance mentally" , "Cause to be mentally unbalanced, like faulty door" , "Drive mad in huge inn" , "Cause to become mentally ill, or detach door" .)