Difficult and tiring (7)
I believe the answer is:
arduous
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">difficult and tiring</span>' is the definition.<br/ ><span class="explanation-format__explanation">(arduous means hard)</span><br/ ><br/ >This is the entire clue.<br/ ></span>
(Other definitions for arduous that I've seen before include "Burdensome" , "Tough" , "Demanding great effort" , "Punishing" , "Backbreaking" .)