Do surgery (7)
I believe the answer is:
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">do surgery</span>' is the definition.<br/ ><span class="explanation-format__explanation">(I've seen this in another clue)</span><br/ ><br/ >This is all the clue.<br/ ></span>
(Other definitions for operate that I've seen before include "Carry on business" , "Work, run" , "(Of machine) function" , "effect" , "Perform as surgeon does" .)