Exasperates (5)
(Other definitions for riles that I've seen before include "Irritates, nettles" , "Annoys in American way" .)
(Another definition for vexes that I've seen is " Annoys".)
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">exasperates</span>' is the definition.<br/ ><span class="explanation-format__explanation">(I've seen this in another clue)</span><br/ ><br/ >This is the entire clue.<br/ ></span>
(Other definitions for irks that I've seen before include "Annoys, vexes" , "'Irritate, annoy (4)'" , "Galls" , "Annoys, irritates" .)
(Other definitions for angers that I've seen before include "annoys" , "Winds up" , "Irritates" , "Outrages" , "Maddens" .)