Follow some men and a girl (5)
I believe the answer is:
ensue
'follow' is the definition.
(ensue can mean to follow or happen as a result)
'some men and a girl' is the wordplay.
'some' says to take the centre.
'and' becomes 'n' (common abbreviation for 'and').
'a girl' becomes 'sue' (girl's name).
The middle of 'men' is 'e'.
'e'+'n'+'sue'='ENSUE'
(Other definitions for ensue that I've seen before include "Cultivate plants/vegetables" , "Occur as a result (of)" , "Transpire" , "Come to pass" , "Follow subsequently" .)