Friend and I leave after mum comes around (5)
I believe the answer is:
amigo
'friend' is the definition.
('friend' in Spanish)
'i leave after mum comes around' is the wordplay.
'leave' becomes 'go' (to go is to depart or leave).
'after' is a charade indicator (letters next to each other).
'mum' becomes 'ma' (both can mean mother).
'comes around' is a reversal indicator.
'ma' reversed gives 'am'.
'i'+'go'='igo'
'igo' after 'am' is 'AMIGO'.
'and' is the link.
(Other definitions for amigo that I've seen before include "Mexican friend" , "Mexican's mate" , "buddy abroad?" , "friend from Barcelona" , "Friend in Spanish-speaking areas" .)