Go back again with a man-eater (4)
I believe the answer is:
ogre
'a man-eater' is the definition.
(I've seen this before)
'go back again' is the wordplay.
'back' shows that the letters should be reversed in order.
'again' becomes 're' (prefix meaning 'again').
'go' reversed gives 'og'.
'og'+'re'='OGRE'
'with' is the link.
(Other definitions for ogre that I've seen before include "Fierce giant" , "Bugbear" , "ugly one" , "Man-eating monster of fairy tales" , "Terrifying man" .)