Go up in flames (4)
I believe the answer is:
burn
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">go up in flames</span>' is the definition.<br/ ><span class="explanation-format__explanation">(something ignited goes up in flames)</span><br/ ><br/ >This is the entire clue.<br/ ></span>
(Other definitions for burn that I've seen before include "Small stream in Scotland" , "Scottish brook" , "Smart" , "Brand" , "Char" .)