God took drugs (5)
I believe the answer is:
hades
'god' is the definition.
(Hades is an example)
'took drugs' is the wordplay.
'took' becomes 'had' ('have' can be a synonym of 'take').
'drugs' becomes 'es' (E is a term for an ecstasy pill).
'had'+'es'='HADES'
(Other definitions for hades that I've seen before include "Classic hell in the shade" , "The nether world, hell" , "Greek god of the underworld" , "Underworld, hell" , "It's classical hell in the shade" .)