Great pain (5)
I believe the answer is:
agony
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">great pain</span>' is the definition.<br/ ><span class="explanation-format__explanation">(I've seen this before)</span><br/ ><br/ >This is the entire clue.<br/ ></span>
(Other definitions for agony that I've seen before include "Pain, torment" , "Extreme suffering - kind of aunt" , "Intense pain" , "Really severe pain" , "woe" .)