Group imbibing drop of stout will get wasted (4)
I believe the answer is:
lost
'wasted' is the definition.
(similar in meaning)
'group imbibing drop of stout' is the wordplay.
'group' becomes 'lot'.
'imbibing' means one lot of letters goes inside another (imbibe can mean to drink or absorb).
'drop of' indicates taking the first letters (the smallest possible amount of the word).
The initial letter of 'stout' is 's'.
'lot' placed around 's' is 'LOST'.
'will get' acts as a link.
(Other definitions for lost that I've seen before include "Mislaid or strayed" , "TV series!" , "See 10" , "Not knowing one's whereabouts" , "Not having known where one is" .)