His associate makes him motherless! (5)
I believe the answer is:
magog
'his associate makes him motherless' is the definition.
The definition suggests a singular noun which matches the answer.
This is the entire clue.
Can you help me to learn more?
(Other definitions for magog that I've seen before include "Gog's companion" , "old giant" , "Last of two old giants" , "Biblical king" , "Gog and -, City of London guardian giants" .)