I fret less with files organised into spreads individually (4-10)
I believe the answer is:
self-fertilises
'spreads individually' is the definition.
I know nothing about this answer so I can't judge whether this works.
'i fret less with files organised' is the wordplay.
'with' means one lot of letters go next to another.
'organised' is an anagram indicator.
'i'+'fret'+'less'+'files'='ifretlessfiles'
'ifretlessfiles' anagrammed gives 'SELF-FERTILISES'.
'into' acts as a link.
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