If you hamper me, I'm deep in distress (6)
I believe the answer is:
impede
'if you hamper me' is the definition.
I can't judge whether this definition defines the answer.
'i'm deep in distress' is the wordplay.
'in distress' indicates anagramming the letters.
'deep' is an anagram of 'pede'.
'im'+'pede'='IMPEDE'
Can you help me to learn more?
(Other definitions for impede that I've seen before include "Delay progress of (something)" , "Delay or obstruct" , "Obstruct, hold up progress" , "Delay; block progress of" , "Hinder, be obstructive" .)