Inclination of a disheartened saint to get out of Leatherhead (5)
I believe the answer is:
slant
'inclination' is the definition.
(slant is a kind of inclination)
'a disheartened saint to get out of leatherhead' is the wordplay.
'a' becomes 'an'.
'disheartened' says to hollow out the word (remove centre letters) (the middle or heart is removed).
'to get' indicates putting letters inside.
'out of' indicates putting letters inside (some letters on the outside of others).
'leatherhead' becomes 'l' (head letter of 'leather').
'saint' with its centre removed is 'st'.
'an' put into 'st' is 'sant'.
'sant' going around 'l' is 'SLANT'.
'of' is the link.
(Other definitions for slant that I've seen before include "Point of view; slope" , "Viewpoint; slope" , "Lean, point of view" , "Slope - bias" , "Angle; make oblique" .)