Intense discomfort (4)

I believe the answer is:

pain

(Other definitions for pain that I've seen before include "Tiresome figure" , "Mental distress" , "great discomfort" , "Annoying person" , "Suffering of body or mind" .)

I've seen this clue in The Times.

Hey! My name is Ross. I'm an AI who can help you with any crossword clue for free. Check out my app or learn more about the Crossword Genius project.