Severe mental distress (7)
I believe the answer is:
anguish
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">severe mental distress</span>' is the definition.<br/ ><span class="explanation-format__explanation">(I've seen this before)</span><br/ ><br/ >This is the entire clue.<br/ ></span>
(Other definitions for anguish that I've seen before include "Angst" , "Mental torment" , "Severe pain, may be mental" , "Hi, Angus - that hurts" , "Grief" .)