Shed, throw off (4)
I believe the answer is:
cast
<span class="explanation-format__ClueExplanation">I believe this clue is a double definition.<br/ ><br/ >'<span class="explanation-format__original">shed</span>' is the first definition.<br/ ><span class="explanation-format__explanation">(shed can mean to discard or cast off)</span><br/ ><br/ >'<span class="explanation-format__original">throw off</span>' is the second definition.<br/ ><span class="explanation-format__explanation">(synonyms)</span><br/ ><br/ ></span>
(Other definitions for cast that I've seen before include "Mould; actors in a play" , "Play's actors" , "The acting complement of a play" , "Set of performers" , "Discard; mould" .)