Crossword Genius

Significant advance (12)

Ross

I believe the answer is:

breakthrough

<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">significant advance</span>' is the definition.<br/ ><span class="explanation-format__explanation">(I've seen this before)</span><br/ ><br/ >This is all the clue.<br/ ></span>

(Other definitions for breakthrough that I've seen before include "Sudden significant development" , "Find" , "Important development (eg in research)" , "(At last!) the solution, eg to scientific problem" , "Significant discovery - ending of impasse" .)

I've seen this clue in The Guardian.
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