Single-celled organism (6)
I believe the answer is:
amoeba
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">single-celled organism</span>' is the definition.<br/ ><span class="explanation-format__explanation">(I've seen this before)</span><br/ ><br/ >This is all the clue.<br/ ></span>
(Other definitions for amoeba that I've seen before include "Microscopic organism consisting of a single cell changing constantly" , "Simplest animal form" , "Tiny organism consisting of single changing cell" , "O, Mam, be a one-celled animal" , "Microscopic animal found in water" .)