Smartly-dressed salesperson home, laid up (6)
I believe the answer is:
dapper
'smartly-dressed' is the definition.
(I've seen this before)
'salesperson home laid up' is the wordplay.
'salesperson' becomes 'rep' (sales rep).
'home' becomes 'pad' (pad can mean someone's home).
'laid up' is a reversal indicator.
'rep'+'pad'='reppad'
'reppad' back-to-front is 'DAPPER'.
(Other definitions for dapper that I've seen before include "Smartly dressed" , "Of man, neat and smart" , "Neat and trim in dress" , "angler letting bait bob on water?" , "Spruce in bearing" .)