Soothing application (4)
I believe the answer is:
aloe
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">soothing application</span>' is the definition.<br/ ><span class="explanation-format__explanation">(I've seen this in another clue)</span><br/ ><br/ >This is the entire clue.<br/ ></span>
(Other definitions for aloe that I've seen before include "Bitter drug from a leaf juice" , "Succulent plant (may be bitter!)" , "O, ale with bitter plant" , "Bitter fruit" , "shrub" .)