Space devoid of matter (6)
I believe the answer is:
vacuum
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">space devoid of matter</span>' is the definition.<br/ ><span class="explanation-format__explanation">(I've seen this in another clue)</span><br/ ><br/ >This is the entire clue.<br/ ></span>
(Other definitions for vacuum that I've seen before include "Space containing no matter" , "Does it take up" , "There's nothing in it" , "A region empty of matter" , "Absence of matter" .)