Started, for instance, during Prohibition (5)
I believe the answer is:
began
'started' is the definition.
('begin' can be a synonym of 'start')
'for instance during prohibition' is the wordplay.
'for instance' becomes 'eg' (short for 'exempli gratia', 'for example' in Latin).
'during' is an insertion indicator.
'prohibition' becomes 'ban' (ban is a kind of prohibition).
'eg' going inside 'ban' is 'BEGAN'.
(Another definition for began that I've seen is " Commenced, started".)
I've seen this clue in the Evening Standard.
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