Such a nuisance writing an advertising slogan for a cigarette! (4,1,3)
I believe the answer is:
what a fag
'such a nuisance writing' is the definition.
I don't know anything about this answer so I cannot judge whether this works.
'advertising slogan for a cigarette' is the wordplay.
'advertising slogan' becomes 'what' (I can't justify this - if you can you should believe this answer much more).
'for' says to put letters next to each other.
'cigarette' becomes 'fag' (synonyms).
'what'+'a'+'fag'='WHAT A FAG'
'an' is the link.
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