Suffer in the wake of hot weather (4)
I believe the answer is:
hail
'weather' is the definition.
(hail is a kind of weather)
'suffer in the wake of hot' is the wordplay.
'suffer' becomes 'ail' (ailing is a kind of suffering).
'in the wake of' is a charade indicator (letters next to each other) (some letters go after others).
'hot' becomes 'h' (abbreviation eg on taps).
'ail' after 'h' is 'HAIL'.
(Other definitions for hail that I've seen before include "Ave - it's frozen rain" , "Greet(ing) - frozen shower" , "weather forecast?" , "Welcome - sort of shower" , "volley" .)