That is the question! (2,2,2,3,2,2)
I believe the answer is:
to be or not to be
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">that is the question</span>' is the definition.<br/ ><span class="explanation-format__explanation">(I've seen this in another clue)</span><br/ ><br/ >This is the entire clue.<br/ ></span>
(Other definitions for to be or not to be that I've seen before include "It was the question for 13 (2,2,2,3,2,2)" , "Mel Brooks' 1983 remake? That is the question!" , "Hamlet's question (2,2,2,3,2,2)" , "Famous line from Hamlet (2,2,2,3,2,2)" , "Shall I commit suicide?" .)