The Royal Family's flatulence painful? Take drug! (7)
I believe the answer is:
windsor
'the royal family's' is the definition.
(Windsor is an example)
'flatulence painful? take drug' is the wordplay.
'flatulence' becomes 'wind'.
'painful?' becomes 'sore' ('sore' can be similar in meaning to 'painful').
'take' suggests deleting specific letters.
'drug' becomes 'e' (E is another name for ecstasy).
'sore' with 'e' removed is 'sor'.
'wind'+'sor'='WINDSOR'
(Other definitions for windsor that I've seen before include "Weekend residence of the British royal family" , "Thames town" , "Town with royal castle" , "Noble family" , "somewhere in Berkshire" .)