TV programme is real stupid (6)
I believe the answer is:
serial
'tv programme' is the definition.
(television serial)
'is real stupid' is the wordplay.
'stupid' indicates an anagram (in a stupid order).
'is'+'real'='isreal'
'isreal' with letters rearranged gives 'SERIAL'.
(Other definitions for serial that I've seen before include "In a sequence" , "appearing at regular intervals" , "Consecutive, sequential" , "Continuous, perhaps like mulitple killer ( 6)" , "Programme appearing in regular instalments" .)