Twisted a twin boy (6)
I believe the answer is:
twined
'twisted' is the definition.
(synonyms)
'a twin boy' is the wordplay.
'boy' becomes 'Ed' (short for Edward).
'twin'+'ed'='TWINED'
(Other definitions for twined that I've seen before include "Wound" , "Wrapped around or coiled" , "Interlaced" , "Wrapped around like string" .)