Upset, agitate (7)
I believe the answer is:
disturb
<span class="explanation-format__ClueExplanation">I believe this clue is a double definition.<br/ ><br/ >'<span class="explanation-format__original">upset</span>' is the first definition.<br/ ><span class="explanation-format__explanation">(synonyms)</span><br/ ><br/ >'<span class="explanation-format__original">agitate</span>' is the second definition.<br/ ><span class="explanation-format__explanation">(synonyms)</span><br/ ><br/ ></span>
(Other definitions for disturb that I've seen before include "Intrude on" , "Unsettle, discomfit" , "Interrupt; upset" , "Agitate - ruffle - trouble" , "Discompose" .)