When the working week comes to a close, they're palsy-walsy! (7)
I believe the answer is:
friends
'when the working week comes' is the definition.
I can't judge whether this definition defines the answer.
'close they're palsy-walsy' is the wordplay.
I cannot really see how this works, but
'close' could be 'end' (close can mean to end or finish) and 'end' is present in the answer.
The remaining letters 'fris' is a valid word which might be clued in a way I don't understand.
This may be the basis of the clue (or it may be nonsense).
'to a' is the link.
Can you help me to learn more?
(Other definitions for friends that I've seen before include "Chums" , "Pals, comrades" , "Intimates" , "playmates!" , "American sitcom" .)