With following wind in last flight (8)
I believe the answer is:
stairway
'flight' is the definition.
(flights of stairs)
'with following wind in last' is the wordplay.
'with' becomes 'w' (short for with).
'following' is a charade indicator (letters next to each other).
'wind' becomes 'air' (air is a kind of wind).
'in' means one lot of letters goes inside another.
'last' becomes 'stay' (I've seen this before).
'w' put after 'air' is 'airw'.
'airw' inserted into 'stay' is 'STAIRWAY'.
(Other definitions for stairway that I've seen before include "- to Heaven, Led Zeppelin song" , "A flight of fixed indoor steps" .)