A bit isolated (5)
I believe the answer is:
apart
'isolated' is the definition.
(I know that isolated can be written as apart)
'a bit' is the wordplay.
'bit' becomes 'part' (I've seen this before).
'a'+'part'='APART'
(Other definitions for apart that I've seen before include "in isolation" , "in bits" , "aloof" , "Unconnected" , "set aside" .)