A complaint I'd not put in a guide (4)
I believe the answer is:
ague
'a complaint' is the definition.
(ague is a kind of health problem)
I don't understand the remainder of the clue.
Can you help me to learn more?
(Other definitions for ague that I've seen before include "Hot and cold fever" , "attack" , "Burning fever" , "Illness with fever and shivering, malaria say" , "Feverish fit" .)