A deadly sin? Absolutely (6)
I believe the answer is:
agreed
'absolutely' is the definition.
(both can be said as affirmative answers)
'a deadly sin?' is the wordplay.
'deadly sin?' becomes 'greed' (greed is a kind of deadly sin).
'a'+'greed'='AGREED'
(Other definitions for agreed that I've seen before include "Jointly decided" , "Consented and concurred" , "Was consistent" , "Assented, acquiesced" , "Did concur" .)