A disease of the eye in which pressure within the eyeball damages the optic disc (8)
I believe the answer is:
glaucoma
(Other definitions for glaucoma that I've seen before include "Eye condition causing weakening or loss of sight" , "Strange to say, a cola mug might cause an eye disease" , "A cola mug, strangely, might give you an eye disease" , "condition of eyeball affecting sight" , "A cola mug, strangely, could give you an eye disease" .)