A female of high note (7)
I believe the answer is:
soprano
'a female of high' is the definition.
'soprano' can be an answer for 'high' (thesaurus). I am not certain of the 'a female of' bit.
'note' is the wordplay.
I cannot really understand how this works, but
'note' could be 'so' (musical note) and 'so' is located in the answer.
This explanation may well be incorrect...
Can you help me to learn more?
(Other definitions for soprano that I've seen before include "Producer of high-pitched sounds" , "(Singer of) the highest vocal range" , "Woman singing" , "gangster" , "Highly vocal musician" .)